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Rhinoplasty consisted of a hump reduction order famvir in united states online, caudal sep- Skin tal shortening famvir 250 mg without prescription, cephalic reduction of the lower lateral cartilages purchase famvir on line amex, ● Thin 25 and infracture. The antiplatelet drugs are most effective at preventing arterial thrombosis, whereas anticoagulants are most effective against venous thrombosis. Dealing effectively with this common problem requires the clinician to understand the potential interactions between the treatment instituted and the underlying pathophysiological process. It is most commonly due to injury to the pregnant or recently pregnant uterus secondary to curettage leading to damage of the endometrial basalis layer. Lidocaine is rapidly inactivated by hepatic enzymes, whereas mexiletine is more slowly Propafenone metabolized and has a longer half-life (see Table 14-2). These salts differ in their percentages of elemental calcium, which must be accounted for when determining dosage. A placent a implant ed in eit her t he anterior, post erior, lat eral, or lower segment of t he uterus does not have the direct angle that a fundally implanted placenta has through the cervix and out the vagina. The cardiac monitor shows irregu- larly, irregular rhyt h m wit h the absence of p-waves. A complet e h ist ory and physical examinat ion, including funduscopic exam- inat ion, auscult at ion of t he major art eries for bruit s, palpat ion of t he abdomen for en larged kidn eys, masses, or an en larged abdomin al aor t a, evaluat ion of the lower ext remit ies for edema and perfusion, and a neurologic examinat ion sh ould be st andard. Only a small fraction is converted into the toxic metabolite through the minor pathway. In addition, there are studies suggesting the avoidance of use of petroleum-based 5. As explained when discussing physiology of erection, the blood fills the vascular sinusoidal spaces of the corpora cavernosa resulting in an erection. Tip overprojection can occur secondary to a displaced tip/ On the other hand, when deprojection with derotation is shield graft. A: Nephrotic syndrome is characterized by generalized oedema, massive proteinuria and hypoalbumi- naemia (with or without hyperlipidaemia). She reports several months of wors- ening fatigue, mild, intermittent, generalized abdominal pain, and loss of appetite with a 10- to 15-lb unintentional weight loss. Recommend dietary modification and prescribe ursodeoxycholate to help dissolve her gallstones E. He is old enough to have reliable neck examination findings and has no evidence of meningeal irritation. B l a c k B o x Wa r n i n g : S u i c i d a l i t y Wi t h A r i p i p r a z o l e Aripiprazole is associated with an increased risk for suicidality in children, adolescents, and your adults with major psychiatric disorders. An u lt r asou n d exam in at ion would con fir m the fet al and amniot ic fluid effect s. The upper third is characterized by short, thick, and Some markers of beauty such as facial symmetry and textural narrow nasal bones that form a more oblique angle at their homogeneity appear to be constant across races and may have apex to span a wider, oval-shaped piriform aperture. Unt reated sept ic arthrit is could lead to rapid dest ruct ion of the joint, so joint aspiration and empiric antibiot ic therapy are appropriate until his cultures and crystal analysis are available. Batten grafts will augment the scroll region as well Adamson and Funk coined the “M-arch” term in an attempt to as the lateral-most aspect of the lateral crura, adding strength integrate nasal tip shape with structural support and dynamic theory. The presence of accelerations, whether occurring spontaneously or in response to contractions, fetal movement, or stimulation of the fetus (either scalp stimulation during a cervical examination or vibroacoustic stimulation using an artifcial larynx) virtually ensures that the ftal arterial pH is greater than 7. However, pharmacologic aids to increase the rate of smoking cessation dur­ ing pregnancy can be used, afer discussion with the patient of the risks and benefts of the medications and of continued smoking. Perhaps one of the biggest advances in managing severely burned patients is the use of early aggressive fluid resuscitation. Relative: • Age: While practice varies, transplants are not routinely done to children (,1 year) or older people (. D emyelin at ion can occu r even wh en fluid rest rict ion is the t reat ment used t o correct the serum sodium level. Joint Examination Examination of the musculoskeletal system should include documentation of inspection, palpation, range of motion, strength, neurovascular status, and, where appropriate, testing specifc fr the involved joint. Migration of bruised cartilage creates asymme- A rocker deformity can be avoided by not extending the tries or irregularities postoperatively. However, if the father is homogygous for ‘d’ then both father and the fetus will be Rh-negative and therefore rhesus disease is said to be unlikely. In severe cases, the pat ient sh ould be h ospit alized and st art ed on int ravenous ant ibiot ics. Superiorly, it attaches to the hyoid bone, mandible, and base of the skull; inferiorly, it attaches to the acromion, clavicle, and manubrium of the sternum. It is reasonable to administer small doses of opioids (fentanyl, morphine) where blunting of respiratory drive is desirable. V V mL mL 800 800 600 600 400 400 200 200 Paw Flow cmH2O L/min 0 0 –10 0 20 40 –100 –50 0 50 Fig. This woman is probably obese and difficult to intubate because of her short neck, and her sleep apnea is a concern. Topiramate Actions and Uses Topiramate [Topamax] is another broad-spectrum antiseizure agent. Later, it was approved for prophylaxis and treatment of atrial flutter and fibrillation, but only if symptoms are severe. Advise patients to report signs of heart failure such as shortness of breath and orthopnea, fatigue, and edema. Subacute toxicity Administer the drug for 90 days in two species via a Behavioral and physiologic changes, blood chemistry levels, route intended for humans. Before glucocorticoid treatment, bone mineral density of the lumbar spine should be measured. In this example, achieving pain relief with meperidine requires higher doses than with morphine. The following are recommendations: When a patient reports a history highly suggestive of anaphylaxis, penicillin and cephalosporins should be avoided. In using conchal cartilage for dorsal onlay is the inability to carve the revision rhinoplasty group, overresection of the caudal dor- this cartilage precisely, postoperative re-curvature, and visibil- sum and underresection of the caudal septum were the two ity through thin skin. The bony rasp is often used for Theoretically, 50 to 60% of the distance from the alar crease to smaller bony humps or for fine dorsal contouring. Excessive postoperative non-surgical bleeding is related to platelet dys- function, impaired coagulation, and i fbrinolysis. The intensity and duration of the abstinence syndrome are determined in part by the duration of drug use and in part by the half-life of the drug taken. Romidepsin binds with receptors for estrogen and can thereby reduce the effects of estrogen-containing contraceptives. St er eot act ic cor e n eed le biop sy r eveals in filt r at in g du c- tal carcinoma. A raised or rising lactate should thus precipitate a careful diagnostic review for signs of circulatory insufciency but, by itself, is not diagnostic of an adverse situation. Options C (E) blockade of calcium channels (blockade of β-adrenoceptors) and E (blockade of calcium 4.

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Dry or moist: • Dry—Dehydration quality famvir 250 mg, mouth breathing buy cheap famvir 250 mg on-line, xerostomia (in Sjogren’s syndrome) generic 250mg famvir mastercard, anticholinergic drug therapy. Depressant effects such as drowsiness, lightheadedness, and fatigue pose a danger if patients engage in hazardous activities. A: The following questions should be asked: • Do your fngers change colour on exposure to cold? It also may be acquired parent erally, such as by intravenous drug use, and during birth from chronically infected moth- ers. For the first 7 weeks of gestation, the placenta depends entirely on progesterone from the corpus luteum. Soft tissue pollybeaks are more troublesome, and scar tissue may need to be excised at revision surgery followed by interval steroid (triamcinolone) injections. If it is not given before 72 hours, every efort should still be made to administer the anti-D IgG, as a dose given within 10 days may provide some protection. All of these are the result of reduced fat absorption, and all can be minimized by reducing fat intake. Lower rebleeding rates and improved survival have been reported with band ligation. Most commonly performed x-ray procedures, including dental, chest, and extremity x-rays, exose a ftus to only very small factons of this amount of radiation. It is highly specific in identifying individuals who will develop periopera- tive cardiac complications B. The patient was doing well but returned to the emergency department with abdominal pain and vomiting. A radiolo- gist has been called to cannulate and embolize the artery supplying the ulcer. Em e r g i n g Co n c e p t s Chromosomal testing and prognostic markers can be used for prognosis. So, chloroquine 600 mg weekly should be given, continued until delivery and breast-feeding are completed. Before starting opioid therapy for chronic pain, clinicians should establish treatment goals with all patients, including realistic goals for pain and function, and should consider how therapy will be discontinued if benefits do not outweigh risks. Headaches and fatigue affect about 20% of patients when given in combination with ribavirin. Diagnostic test: Echocardiogram to assess the aortic valve area as well as the left vent ricular syst olic funct ion. As the lateral crura the periosteum to the midline and no higher than the medial are repositioned into a more caudal orientation, they are pivoted canthi to preserve this tight pocket. The results of her physical examination were unremarkable, and no cardiac abnormalities were identified. The most recent clinical report from the American Academy of Pediatrics concerning conditions affecting sports participation references the 3rd International Conference on Concussion in Sports from 2008. While this patient will most likely require transfer to a hospital equipped to handle burn victims, the first step is to stabilize the patient. His past medical history reveals multiple episodes of otitis media and pneumonia, and he has now developed severe nose bleeds. Care must be taken, especially in revision rhinoplasty, to directly posterior to desired tip-defining point and is oriented preserve the integrity of the overlying lateral crura as they are in the plane of the dome truncation. Many newer studies on quality of life and nasal surgery have shown a less esoteric but persistent impact of the nose on a patient’s overall psychological health. There must be a judicious tive nasal defects: managing the “near-miss” rhinoplasty. Sodium restriction combined with a thiazide diuretic can enhance intestinal absorption of calcium and can decrease urinary excretion of calcium. Instruction should include cognitive coping skills and information on relaxation techniques (e. Termination of Transmitter Action Drugs can interfere with the termination of transmitter action by two mechanisms: (1) blockade of transmitter reuptake and (2) inhibition of transmitter degradation. Ferrous 168 Chapter 17 y Hematopoietic Drugs 169 administration of iron dextran can cause adverse reactions Ingested iron at the injection site, including pain, infammation, sterile Myoglobin and enzymes abscesses, and brown discoloration of skin. None of these offers all of the benefits of estrogen, and none avoids all of the drawbacks. As sildenafl inhibits phosphodiester- ripening before induction of labor and for evacuation ase type 5, an increase of cyclic guanosine monophosphate of the uterine contents. However, a reduction in microvascular complications (especially retinal damage) accounted for most of the benefit. This morning at work, he noticed vertigo, then light- headedness, then lost consciousness for a few seconds. Montelukast, a Leukotriene Antagonist Montelukast [Singulair], originally approved for asthma, is now approved for seasonal and perennial allergic rhinitis as well. Actual cause is unknown, probably due to upregulation of opioid receptors and increased levels of endogenous opioids. Exemestane is rapidly absorbed after oral dosing and is widely distributed to tissues. Four ferrous iron salts are available: ferrous sulfate, ferrous gluconate, ferrous fumarate, and ferrous aspartate. Note the asymmetrical resection of the nasal hump as a monoblock and two spreader grafts set laterally along the anterosuperior septal border. It is imp or t ant for the pat ient an d ph y- sician t o have realist ic expect at ions about surgical t reat ment out come. H owever, empiric treatment should be initiated with a third-generation cephalosporin (ceftriaxone, cefotaxime) while awaiting cul- ture results given the most common cause is gram-negative organisms. On physical examination, the pupils demonstrate equal size and reactivity and react to light and accommodation. Cerebellar lesions are usually bilateral (unilateral lesion is against paraneoplastic cerebellar lesion). Delayed cord clamping also improves iron st ores in t erm infant s, but may also lead t o a higher risk of hyperbilirubinemia. A large negative P wave seen in lead V1 is also indicative of left atrial enlargement. Palpation: • Trachea is central, tracheal tug (descent of trachea during inspiration) is present. The role of adjuvant radiation and/ or chemotherapy remains unclear in this patient population. Primary care providers need to be prepared to monitor for outcomes or adverse effects that may indicate a need for a change in management. The subjective assessment should include the onset, lateral crus, induding the fibrofatty tissue, which extends to the history of trauma (including surgery), duration, exacerbating bony piriform aperture.

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Cimetidine suppresses basal acid secretion and secretion stimulated by gastrin and acetylcholine discount 250 mg famvir. The keys in this patient’s history are t he persistent low-grade feelings of dysequilibrium and the finding of probable sensorineural hearing loss on the left side buy famvir 250 mg with visa. If these Allopurinol and its active metabolite purchase 250 mg famvir otc, oxypurinol (also drugs do not provide relief or cannot be tolerated by the called alloxanthine), decrease the production of uric acid by patient, colchicine can be given orally or parenterally. For example, hepatic inactivation of isoniazid is rapid in some people and slow in others. Dissection and Urinary tract infection – Persistent vaginal discharge – rule out fbroid pseudoaneurysm very rare expulsion. Aspirin soon slow its absorption rate, it does not signifcantly reduce its became widely used around the world as an analgesic, anti- bioavailability. Incision in the mucous zontal strip resections are required when the septum is too membrane should be avoided if possible because heavy bleeding high. Management includes dialysis and correction of fluid and electrolyte abnormalities. Consequently, the length of tracheostomy tube that is intrastomal rather than intratracheal will vary. However, if dosing is done with or shortly after a meal, both the rate and extent of absorption can be significantly lowered. Atracurium, cisa­ receptors in skeletal muscle, and this accounts for their tracurium, rocuronium, and vecuronium provide an inter- muscle-relaxing effects. Patient comfort should improve (decreased respiratory rate, heart rate, blood pressure, agitation, and sedation requirements). These drugs have little or no effect on the release of epinephrine from the adrenal medulla. Dissection graft can be undertaken to prevent graft movement and warp- is carried medial to the natural domes onto the medial crura, ing. Patients should be taught that physical dependence is not the same as addiction and that physical dependence itself is nothing to fear. Pharmacokinetics When taken on an empty stomach, absorption is rapid and peak time is 0. For this reason, tetracycline preparations must be used Azithromycin is also active against pathogens or discarded by their expiration date. Sixty-two (86%) patients reported improvement in the appearance of their noses, 8 (11%) patients believed that their appearance was unchanged, and 2 (3%) patients believed that the appearance of their noses was made worse by the procedure. It is important to identify those at the highest risk of mortality prior to listing, as Ctx has a -year mortality of 75%. She brings with her the results of a private urodynamic study that she had done after surfing the Internet. However, once appendicitis seems likely, surgical management should occur in a timely fashion; perforation rates exceed 65% if diag- nosis is delayed beyond 36 to 48 hours from symptom onset. The signs and symp- toms of kernicterus may be subtle and similar to those of sepsis, asphyxia, hypoglycemia, and intracranial hemorrhage. The general properties of these drugs are described in • In addition to analgesia, opioid agonists can cause Chapter 20. A high- fat meal slows absorption, resulting in a peak plasma level in 2 hours (rather than 1) and reducing the peak concentration. Neurological profile of the sacral nerves Match the following sin gle b est t h er ap y ( A-G ) that will m ost likely h elp in the clin i- cal situat ion described (35. Cultures of the purulent drainage would most likely reveal which of the fol- lowing? He reports difficulty in getting out of bed in the morning and may have to roll out sideways, trying not to flex or rotate the spine to minimize pain. The distracter is induction of labour before term but we prefer not to induce women with section scars as the drugs used increase the risk of scar rupture. It only meas- ures pulsatile flow, so it is not affected by static signals (such as those from venous or capillary blood). H pylori is associat ed wit h 30% to 60% of gast ric ulcers and wit h 50% to 70% of duodenal ulcers. A Foley cat h et er for cont inu ou s u r in e out put m on it or in g, ser ial ar t er ial blood gas m easu r e- ments for trends in base deficit and lactate levels, and arterial catheterization for cont in u ou s blood pr essu r e m easu r em en t s can b e h elpfu l. These spaces are lined with respiratory mucosa, decrease the weight of the skull, and probably assist in humidifying inspired air. Distinguish “benign” positional vertigo from more serious central causes of ver t igo. My diagnosis is peripheral vascular disease, more likely Buerger’s disease (in young patient). Rifampicin 300 mg/day or naltrexone (opioid antagonist) 25 mg/day up to 300 mg/day may be given. The bad news is that, because triazolam is rapidly cleared, treatment is associated with two problems: (1) tolerance to hypnotic effects can develop quickly—in 11 to 18 days, which is much faster than with other benzodiazepines; and (2) triazolam causes more rebound insomnia than other benzodiazepines. The drug is given to treat acute keratoconjunctivitis and recurrent epithelial keratitis. Extra-pulmonary manifestations • Renal angiomyolipomas (benign tumours made up of adipose tissue, smooth muscle cells, and thickened blood vessels). A calculation that meets or exceeds 200 Montevideo units is commonly accepted as an adequate uterine contraction pattern (Figure 1– 2). Screening for hepatitis C, cytomegalovirus, toxoplasmosis, group B streptococcus, chlamydia, and asymptomatic bacterial vaginosis should not be ofered as part of routine antenatal care. Adverse Effects The most serious adverse effects result from blockade of beta receptors in the1 heart and blockade of beta receptors in the lungs. However, a causal relationship between these events and mifepristone/misoprostol has not been established. To achieve an extended schedule, the user would simply purchase four packets of a 28-day product (each of which contains 21 active pills) and then take the active pills for 84 days straight. Now, three agents—cetirizine, fexofenadine, and loratadine—are available over the counter. Prednisone (a glucocorticoid) is given to reduce inflammation during larval migration. In contrast to vitamin B12, folic acid is not conserved rigidly: every day, significant amounts are excreted. Remissions have been prolonged in some patients, and resistance has not been reported. A narrow and tight pocket is created just and decreases tip bulbosity when correction is resistant to caudal to the marginal incision and a thin strip of cartilage is placed and secured. Patients with chronic wounds including burn scars are at risk ofdeveloping malignance transformation in the chronic wounds. The answer is E: is a selective benzodiazepine antago- (C) increasing slow-wave sleep nist. The localization of the deformity, excellent exposure and isolation of septum separates the two sides of the nose and stabilizes the the septal L-strut, and meticulous technique.

A crude drug preparation retains that contain nitrogen groups and produce an alkaline reac- most or all of the active and inactive compounds contained in the natural tion in aqueous solution order 250mg famvir with visa. Specific vaccinations are available for H influenzae type B and some strains of S pneumoniae and are now rout inely admin- ist ered t o children purchase 250 mg famvir fast delivery. T h ey are t r eat ed wit h defibrillation purchase famvir online from canada, followed by in fu sion of intravenous antiarrhythmics such as amiodarone. Thus, a thorough the nasal tip is often thicker when compared with that of the understanding of these concepts and how they impact upon one’s leptorrhine nose. A high-fiber diet rich in fresh fruits and vegetables, low in cholesterol, saturated fats, and refined sugars should be instituted. Athelet ic acit ivies wit h t he highest reported incidences of concussions are foot ball, h ockey, soccer, r ugby, an d basket ball. Be able to describe the origin, course, muscles innervated, and distal cutaneous regions supplied by the radial nerve 2. Taken together, these guidelines suggest that most patients with diabetes should receive a statin. With two diseases, results have been even more dramatic: wild-type polio is gone from the Western hemisphere, and smallpox is gone from the planet. Routine annual screening mammography is recom- mended for women over the age of 40. In the normal anatomic situat ion, t he uret hral pressure exceeds the bladder pressure, and also the pelvic diaphragm supports the bladder and urethra. Melanoma is the fifth most common cancer in men and the seventh most common cancer in women in the United St ates. Interfaces are therefore interchangeable in clinical practice, although adjustment of the ventilator settings may be required. Ac u t e Ch o l e c y s t i t i s A common physiologic effect of pregnancy is an increase in gallbladder volume and biliary sludge (especially after the first trimester). This pat ient most likely has ischemic colitis, which is the most common form of intestinal ischemia. Unfortu- nately, there is no clear evidence available to indicate the optimal time when biliary decompression procedures should be accomplished. An attempt should be made to quan- favorable position with bony vault repositioning. If t hese are normal, t hen t he next step is typically to assess luteinizing hormone and follicle-stimulat- ing hormone and administer progest in to see if t he outflow t ract (uterus) responds normally and has sufficient estrogen to have caused prolifera- tion of the endometrium (see Cases 49-51; Case 49 contains a diagnostic algorit hm). For t he student, knowing exact dosages is not as import ant as under- st anding t he best medicat ion, rout e of delivery, mechanism of act ion, and possible complicat ion s. The glucocorticoid has the added benefit of decreasing pain by reducing swelling caused by inflammation. Men are more commonly afected on the upper torso, whereas women are afected mostly on the legs. Most patients with • Corticosteroids, the most effcacious antiinfammatory mild symptoms can be adequately treated with an antihista- drugs, are usually given by inhalation on a long-term mine drug alone, but patients with moderate to severe basis to prevent asthmatic attacks. Be able to describe the course and areas of the heart supplied by the right and left coronary arteries, respectively 2. Drugs simply make conditions favorable for overgrowth of microbes that have acquired mechanisms for resistance. The safest antidote for cyanide toxicity is intravenous hydroxocobalamin, which combines with cyanide to form cyanocobalamin (vitamin B1 ),2 which is subsequently excreted by the kidneys. These studies can be nonspecific and in the case of ultrasound, operator-dependent. In addition, about 11,000 victims were hospitalized each year, and about 100 died. It is used as intranasal spray or administered by subcutaneous injection in women with Von Willebrand disease. These at acetylcholine synapses, and the atropine dosage must be drugs are typically used to produce mydriasis and facilitate titrated to the patient’s response. It is imp or t ant t o n ot e that the ph ysical examin at ion is n ot always r eli- able, as t he result of dist ract ing injuries and h ist ory of hallucinogen and/ or alcoh ol con su mp t ion. Training for prescribers focuses on patient selection, balancing the risks and benefits of opioids, monitoring treatment, and recognizing opioid misuse, abuse, and addiction. A portion of breast tissue typi- cally extends into the axilla as the axillary tail (of Spence). Whether to place tain anatomic and cultural traits can be generalized to help the another implant or not during the operation would fall under prospective surgeon approach the Asian patient. Papillomatosis wit hout at ypia is not associat ed wit h t he increase in cancer risk; h owever, papillomat osis wit h at ypia carries a 4- t o 5-fold increase in breast cancer risk. For example, Kridel et al12 described the lateral crural steal skin-soft tissue envelope, long upper lateral cartilages, or an technique in which the lateral crus of the lower lateral cartilage abnormal caudal septum. Use systemic beta agonists with 2 caution in patients with diabetes, hyperthyroidism, organic heart disease, hypertension, or angina pectoris. The sequence is begun on either (1) the first day of the menstrual cycle or (2) the first Sunday after the onset of menses. The open technique has developed rap- idly in the last 30 years and has led to the new techniques and trends. Chapter 20 y Antiepileptic Drugs 201 3 Nitric + 1 oxide Glu 2 Ca2+ Ca2+ Spikelets Long-term potentiation Seizure focus Frontal lobe Normal Abnormal Depolarization shift Synchronization of adjacent neuronal discharges Seizure Figure 20-2. Gestational diabetes is managed in much the same manner as any other diabetic pregnancy: blood glucose should be monitored and then controlled with diet and insulin. The albuterol was inadvertently left out of the inhalation treatment, and the girl received only saline. The alae, nasalis muscle, depressor septi nasi ment of the length of the nose, the nasolabial angle, and the muscles, and upper lip also play a role. Although the patient in t he scenario, like most lupus pat ient s, sought medical att ent ion because of t he pain of arthritis or serositis, both these problems are generally manageable or self- limit ed. W ith his current picture, it is not unreasonable to init iat e broad-spect rum ant imicrobial t herapy t arget ing G I t ract microbial flora. Co n s i d e r a t i o n s This 29-year-old woman delivers at 39 weeks’gestation and has an estimated blood loss of 1000 cc aft er the placent a delivers. This may be achieved with other techniques as well, and the columellar strut was reported not to be essential to maintain or enhance tip projection and rotation. Five of these drugs are available: imatinib, dasatinib, bosutinib, ponatinib, and nilotinib. Typically, the patient will not move the arm and will support the limb flexed at the elbow with the opposite hand. Differences relate to side effects, especially thrombotic events, androgenic effects (acne, hirsutism, dyslipidemia), and hyperkalemia. He is afebrile, heart rate is 115 b p m with a thread y p ulse, resp iratory rate 22 b reaths p e r minute, and blood pressure 108/86 mm Hg. However, in contrast to the aminoglycosides, these agents only slow microbial growth—they do not kill bacteria at clinically achievable concentrations. However, pharmacological sedation should be used cautiously, since confusion and agitation may also be caused by hypoxia and hypercapnia.

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